Eleven-year-old Luke, a hardcore fan of comics and superheroes, is jealous when his undeserving older brother Zack is zapped by an alien and turned into a superhero, until a plot to destroy the Earth incapacitates Zack, and Luke, accompanied by Lara, the nosey girl next door, must come to the rescue.

After an encounter with a sparrow, Henry finds he is able to fly just like his favorite comic book hero HawkMan.

Buzz creates a comic book that features Buzz Boy and Fly Guy as the superheroes.

When Professor Pippy P. Poopypants comes to Jerome Horwitz Elementary School to teach science, and he goes off the deep end because students make fun of his name, only Captain Underpants can save the school from the professor's perilous plot.

Eastwood Elementary's new student is nothing like the other kids in 3G. Fangbone is a barbarian warrior from another world, he's been charged with the task of keeping a deadly weapon from Skullbania's vilest villain, Venomous Drool. Can Fangbone's new classmates team up to help him triumph over hound-snakes, lava-ferrets, and his first pop quiz?

George and Harold hypnotize their principal who, believing he is the superhero Captain Underpants, leads them to the lair of the nefarious Dr. Diaper. They must then defeat his evil robot henchmen.