Sixteen-year-old Jacob, having traveled to a remote island after a family tragedy, discovers an abandoned orphanage, and, after some investigating, he learns the children who lived there may have been dangerous and quarantined and may also still be alive.

Since her father's death, Cat has taken care of her brother, Chicken, for their hardworking mother but while spending time with grandparents they never knew, Cat has the chance to be a child again.

Roz the robot discovers that she is alone on a remote, wild island with no memory of where she is from or why she is there, and her only hope of survival is to try to learn about her new environment from the island's hostile inhabitants.