"Memphis, Tennessee, 1936. The five Foss children find their lives changed forever when their parents leave them alone ... one stormy night. Rill Foss ... must protect her four younger siblings as they are wrenched from their home on the Mississippi and thrown into the care of the infamous Georgia Tann, director of the Tennessee Children's Home Society. South Carolina, present day. Avery Stafford has lived a charmed life. Loving daughter to her father,...

Sixteen-year-old Jacob, having traveled to a remote island after a family tragedy, discovers an abandoned orphanage, and, after some investigating, he learns the children who lived there may have been dangerous and quarantined and may also still be alive.