After their lunches are stolen, Harry Buttz Elementary School students Darren, Tina, Juan-Carlos, and Walter eat radioactive burritos that give each a strange ability--along with serious gas--which, with training by Janitor Stan, may help them foil Number Two and the BO twins' evil plan.

Something is rotten in the plumbing of Harry Buttz Elementary School, and it's kidnapped Janitor Stan. It's up to the Fart Squad to dive into the toilet vortex to save their scent-sei from the World of the Royal Flush. Grab a match, because this stink just got real. Only the Fart Squad has the guts, the gall, and the gas to flush this round brown mound before he overflows his toilet kingdom on the world.

When Darren Stonkadopolis claims he's had a close encounter of the stinky kind, the other Fart Squad members think he's full of hot air. But then the alien Stink Weeds descend, and the Fart Squad is forced to smell the truth. It'll take some weed wacking, some stealthy stench tactics, and buttfuls of gas so smelly they'd make the sun blush to stop these mutant extraterrestrial vegetables from universal stinkination.